Nuclear magnetic resonance (NMR) has been celebrated for its ability to determine molecular structures and dynamics at atomic resolution, with a profound impact in organic chemistry, biochemistry, structural biology, and drug discovery. We create silicon NMR spectrometers that can execute a broad palette of multidimensional NMR spectroscopic modalities, and operate them with a superconducting magnet as well as a compact permanent magnet. The aim is to develop translational biomolecular NMR spectroscopy technologies by leveraging the size and cost economy of the silicon NMR spectrometer chips. Particular technologies of interest include: (1) high-throughput pharmaceutical screening and structural biology; (2) high-throughput metabolomics; (3) in-cell NMR; (4) correlated acquisition spectroscopy; and (5) portable NMR spectroscopy.
We investigate nanoscale, low-dimensional, and/or quantum materials, e.g., graphene and other atomic layer materials, quantum wells, wires, and dots of various constructs, and (optically-detected) spin resonance systems. We study electron transport, spin dynamics, topological order, correlated electron behavior and collective excitations, optical properties, and electrochemistry in these materials, and pursue their applications in plasmonics, photonics, spintronics, nano-biotechnology, quantum information as well as (beyond-CMOS) electronics.
Using an electronic and electrochemical platform with many nonlinearly interacting sub systems that are thoroughly open to the external world, we are investigating how to realize complex systems that can manifest collaborative behaviors, leading to emergent collective behaviors with autonomy, adaptivity, self-organization, and memory at the edge of chaos.